Excitotoxins in Neuronal Apoptosis and Necrosis
نویسندگان
چکیده
منابع مشابه
Excitotoxins in neuronal apoptosis and necrosis.
Neuronal loss is common to many neurodegenerative diseases. Although necrosis is a common histopathologic feature observed in neuropathologic conditions, evidence is increasing that apoptosis can significantly contribute to neuronal demise. The prevalence of either type of cell death, apoptosis or necrosis, and the relevance for the progression of disease is still unclear. The debate on the occ...
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This article discusses the various mechanisms, biochemical pathways, and chemical substances involved in neuronal cell death and cell survival, in an attempt to put an order to the sequence of events that ultimately lead to a commitment to neurological cell death. An understanding of these pathways is crucial to discovering etiologies involved in the pathologic changes that occur in patients wi...
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Background: In mammalian ovaries, loss of over two-thirds of germ cells happens due to cell death. Nonetheless, the exact mechanism of cell death has yet to be determined. The present basic practical study was designed to detect 3 types of programmed cell death, namely apoptosis, autophagy, and necrosis, in murine embryonic gonadal ridges and neonatal ovaries.Methods: Twenty gonadal ridges and ...
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Stroke patients comprise a large number of patients with a highly significant degree of cerebral ischemia that is best exemplified by the transient focal ischemia models in experimental animals such as rat and mouse. Mechanisms include bioenergetic failure and loss of cell homeostasis, and also acidosis, excitotoxicity and disrupted blood-brain barrier [1]. A central issue is the series of set ...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1999
ISSN: 0271-678X,1559-7016
DOI: 10.1097/00004647-199906000-00001